After engineering a daring escape from the hellish, Panamanian prison Sona, brothers Michael Scofield and Lincoln Burrows are determined to seek justice against The Company, the shadowy group responsible for destroying their lives and killing the woman Michael loves, Dr. Sara Tancredi. Michael’s quest for vengeance leads him to Los Angeles, where his world is turned upside down when Company operative Gretchen/Susan B. Anthony informs him that Sara is still alive. Realizing the only way they will truly be free, Michael and Lincoln avow to find Sara and take down The Company. With the help of Homeland Security agent Don Self, they assemble a group of allies and familiar faces to accomplish their task: Mahone, Sucre, Bellick and computer expert Roland Glenn. Unfortunately for the brothers, they must also evade company assassin Wyatt and find an on-the-loose T-Bag. Michael and Lincoln soon discover the only thing harder than breaking out will be breaking in.
4 - 1Scylla Sep. 01, 2008
4 - 3Shut Down Sep. 08, 2008
4 - 4Eagles and Angels Sep. 15, 2008
4 - 5Safe and Sound Sep. 22, 2008
4 - 6Blow Out Sep. 29, 2008
4 - 7Five the Hard Way Oct. 06, 2008
4 - 8The Price Oct. 20, 2008
4 - 9Greatness Achieved Nov. 03, 2008
4 - 10The Legend Nov. 10, 2008
4 - 11Quiet Riot Nov. 17, 2008
4 - 12Selfless Nov. 24, 2008
4 - 13Deal Or No Deal Dec. 01, 2008
4 - 14Just Business Dec. 08, 2008
4 - 15Going Under Dec. 15, 2008
4 - 16The Sunshine State Dec. 22, 2008
4 - 17The Mother Lode Apr. 17, 2009
4 - 18VS. Apr. 24, 2009
4 - 19S.O.B. May. 01, 2009
4 - 20Cowboys and Indians May. 08, 2009
4 - 21Rate of Exchange May. 15, 2009
4 - 22Killing Your Number May. 15, 2009